Update on GNA Alterations in Cancer: Implications for Uveal Melanoma Treatment

Tumorigenesis is correlated with abnormal expression and activity of G protein-coupled receptors (GPCRs) and associated G proteins. Oncogenic mutations in both GPCRs and G proteins (GNAS, GNAQ or GNA11) encoding genes have been identified in a significant number of tumors. Interestingly, uveal melan...

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Detalles Bibliográficos
Autores principales: Larribère, Lionel, Utikal, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352965/
https://www.ncbi.nlm.nih.gov/pubmed/32532044
http://dx.doi.org/10.3390/cancers12061524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352965/
https://www.ncbi.nlm.nih.gov/pubmed/32532044
http://dx.doi.org/10.3390/cancers12061524

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