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Update on GNA Alterations in Cancer: Implications for Uveal Melanoma Treatment
Tumorigenesis is correlated with abnormal expression and activity of G protein-coupled receptors (GPCRs) and associated G proteins. Oncogenic mutations in both GPCRs and G proteins (GNAS, GNAQ or GNA11) encoding genes have been identified in a significant number of tumors. Interestingly, uveal melan...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352965/ https://www.ncbi.nlm.nih.gov/pubmed/32532044 http://dx.doi.org/10.3390/cancers12061524 |