Anti-EGFR Therapy Induces EGF Secretion by Cancer-Associated Fibroblasts to Confer Colorectal Cancer Chemoresistance

Targeted agents have improved the efficacy of chemotherapy for cancer patients, however, there remains a lack of understanding of how these therapies affect the unsuspecting bystanders of the stromal microenvironment. Cetuximab, a monoclonal antibody therapy targeting the epidermal growth factor rec...

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Detalles Bibliográficos
Autores principales: Garvey, Colleen M., Lau, Roy, Sanchez, Alyssa, Sun, Ren X., Fong, Emma J., Doche, Michael E., Chen, Oscar, Jusuf, Anthony, Lenz, Heinz-Josef, Larson, Brent, Mumenthaler, Shannon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352975/
https://www.ncbi.nlm.nih.gov/pubmed/32481658
http://dx.doi.org/10.3390/cancers12061393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352975/
https://www.ncbi.nlm.nih.gov/pubmed/32481658
http://dx.doi.org/10.3390/cancers12061393

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