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Anti-EGFR Therapy Induces EGF Secretion by Cancer-Associated Fibroblasts to Confer Colorectal Cancer Chemoresistance
Targeted agents have improved the efficacy of chemotherapy for cancer patients, however, there remains a lack of understanding of how these therapies affect the unsuspecting bystanders of the stromal microenvironment. Cetuximab, a monoclonal antibody therapy targeting the epidermal growth factor rec...
Autores principales: | Garvey, Colleen M., Lau, Roy, Sanchez, Alyssa, Sun, Ren X., Fong, Emma J., Doche, Michael E., Chen, Oscar, Jusuf, Anthony, Lenz, Heinz-Josef, Larson, Brent, Mumenthaler, Shannon M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352975/ https://www.ncbi.nlm.nih.gov/pubmed/32481658 http://dx.doi.org/10.3390/cancers12061393 |
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