A H-REV107 Peptide Inhibits Tumor Growth and Interacts Directly with Oncogenic KRAS Mutants

Kirsten-RAS (KRAS) has been the target of drugs because it is the most mutated gene in human cancers. Because of the low affinity of drugs for KRAS mutations, it was difficult to target these tumor genes directly. We found a direct interaction between KRAS G12V and tumor suppressor novel H-REV107 pe...

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Detalles Bibliográficos
Autores principales: Han, Chang Woo, Jeong, Mi Suk, Ha, Sung Chul, Jang, Se Bok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352977/
https://www.ncbi.nlm.nih.gov/pubmed/32486141
http://dx.doi.org/10.3390/cancers12061412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352977/
https://www.ncbi.nlm.nih.gov/pubmed/32486141
http://dx.doi.org/10.3390/cancers12061412

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