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Weak Interaction of the Antimetabolite Drug Methotrexate with a Cavitand Derivative

Formation of inclusion complexes involving a cavitand derivative (as host) and an antimetabolite drug, methotrexate (as guest) was investigated by photoluminescence measurements in dimethyl sulfoxide solvent. Molecular modeling performed in gas phase reflects that, due to the structural reasons, the...

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Detalles Bibliográficos
Autores principales: Preisz, Zsolt, Nagymihály, Zoltán, Lemli, Beáta, Kollár, László, Kunsági-Máté, Sándor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353011/
https://www.ncbi.nlm.nih.gov/pubmed/32570928
http://dx.doi.org/10.3390/ijms21124345