Bromodomain-Containing Protein BRD4 Is Hyperphosphorylated in Mitosis

The epigenetic reader BRD4 binds acetylated histones and plays a central role in controlling cellular gene transcription and proliferation. Dysregulation of BRD4′s activity has been implicated in the pathogenesis of a wide variety of cancers. While blocking BRD4 interaction with acetylated histones...

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Detalles Bibliográficos
Autores principales: Wang, Ranran, Yang, June F., Ho, Flora, Robertson, Erle S., You, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353023/
https://www.ncbi.nlm.nih.gov/pubmed/32575711
http://dx.doi.org/10.3390/cancers12061637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353023/
https://www.ncbi.nlm.nih.gov/pubmed/32575711
http://dx.doi.org/10.3390/cancers12061637

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