Identifying and Overcoming Mechanisms of PARP Inhibitor Resistance in Homologous Recombination Repair-Deficient and Repair-Proficient High Grade Serous Ovarian Cancer Cells

High grade serous ovarian cancer (HGSOC) is a major cause of female cancer mortality. The approval of poly (ADP-ribose) polymerase (PARP) inhibitors for clinical use has greatly improved treatment options for patients with homologous recombination repair (HRR)-deficient HGSOC, although the developme...

Descripción completa

Detalles Bibliográficos
Autores principales: Gomez, Miriam K., Illuzzi, Giuditta, Colomer, Carlota, Churchman, Michael, Hollis, Robert L., O’Connor, Mark J., Gourley, Charlie, Leo, Elisabetta, Melton, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353027/
https://www.ncbi.nlm.nih.gov/pubmed/32526907
http://dx.doi.org/10.3390/cancers12061503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353027/
https://www.ncbi.nlm.nih.gov/pubmed/32526907
http://dx.doi.org/10.3390/cancers12061503

Ejemplares similares