Shallow Whole-Genome Sequencing from Plasma Identifies FGFR1 Amplified Breast Cancers and Predicts Overall Survival

Background: Focal amplification of fibroblast growth factor receptor 1 (FGFR1) defines a subgroup of breast cancers with poor prognosis and high risk of recurrence. We sought to demonstrate the potential of circulating cell-free DNA (cfDNA) analysis to evaluate FGFR1 copy numbers from a cohort of 10...

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Detalles Bibliográficos
Autores principales: Bourrier, Chantal, Pierga, Jean-Yves, Xuereb, Laura, Salaun, Hélène, Proudhon, Charlotte, Speicher, Michael R., Belic, Jelena, Heitzer, Ellen, Lockhart, Brian Paul, Guigal-Stephan, Nolwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353062/
https://www.ncbi.nlm.nih.gov/pubmed/32517171
http://dx.doi.org/10.3390/cancers12061481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353062/
https://www.ncbi.nlm.nih.gov/pubmed/32517171
http://dx.doi.org/10.3390/cancers12061481

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