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Integrin-Targeting Dye-Doped PEG-Shell/Silica-Core Nanoparticles Mimicking the Proapoptotic Smac/DIABLO Protein

Cancer cells demonstrate elevated expression levels of the inhibitor of apoptosis proteins (IAPs), contributing to tumor cell survival, disease progression, chemo-resistance, and poor prognosis. Smac/DIABLO is a mitochondrial protein that promotes apoptosis by neutralizing members of the IAP family....

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Detalles Bibliográficos
Autores principales: De Marco, Rossella, Rampazzo, Enrico, Zhao, Junwei, Prodi, Luca, Paolillo, Mayra, Picchetti, Pierre, Gallo, Francesca, Calonghi, Natalia, Gentilucci, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353088/
https://www.ncbi.nlm.nih.gov/pubmed/32575872
http://dx.doi.org/10.3390/nano10061211