The Hepatotoxicity of Alantolactone and Germacrone: Their Influence on Cholesterol and Lipid Metabolism in Differentiated HepaRG Cells

The sesquiterpenes alantolactone (ATL) and germacrone (GER) are potential anticancer agents of natural origin. Their toxicity and biological activity have been evaluated using the differentiated HepaRG (dHepaRG) cells, a hepatocyte-like model. The half-maximal inhibitory concentrations of cell viabi...

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Detalles Bibliográficos
Autores principales: Zárybnický, Tomáš, Matoušková, Petra, Skálová, Lenka, Boušová, Iva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353089/
https://www.ncbi.nlm.nih.gov/pubmed/32521813
http://dx.doi.org/10.3390/nu12061720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353089/
https://www.ncbi.nlm.nih.gov/pubmed/32521813
http://dx.doi.org/10.3390/nu12061720

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