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High-throughput gene screen reveals modulators of nuclear shape

Irregular nuclear shapes characterized by blebs, lobules, micronuclei, or invaginations are hallmarks of many cancers and human pathologies. Despite the correlation between abnormal nuclear shape and human pathologies, the mechanism by which the cancer nucleus becomes misshapen is not fully understo...

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Detalles Bibliográficos
Autores principales: Tamashunas, Andrew C., Tocco, Vincent J., Matthews, James, Zhang, Qiao, Atanasova, Kalina R., Paschall, Lauren, Pathak, Shreya, Ratnayake, Ranjala, Stephens, Andrew D., Luesch, Hendrik, Licht, Jonathan D., Lele, Tanmay P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353136/
https://www.ncbi.nlm.nih.gov/pubmed/32320319
http://dx.doi.org/10.1091/mbc.E19-09-0520