β-catenin-mediated Wnt signal transduction proceeds through an endocytosis-independent mechanism

The Wnt pathway is a key intercellular signaling cascade that regulates development, tissue homeostasis, and regeneration. However, gaps remain in our understanding of the molecular events that take place between ligand-receptor binding and target gene transcription. We used a novel tool for quantit...

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Detalles Bibliográficos
Autores principales: Rim, Ellen Youngsoo, Kinney, Leigh Katherine, Nusse, Roeland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353137/
https://www.ncbi.nlm.nih.gov/pubmed/32320321
http://dx.doi.org/10.1091/mbc.E20-02-0114