Cargando…

FOXM1 nuclear transcription factor translocates into mitochondria and inhibits oxidative phosphorylation

Forkhead box M1 (FOXM1), a nuclear transcription factor that activates cell cycle regulatory genes, is highly expressed in a majority of human cancers. The function of FOXM1 independent of nuclear transcription is unknown. In the present study, we found the FOXM1 protein inside the mitochondria. Usi...

Descripción completa

Detalles Bibliográficos
Autores principales: Black, Markaisa, Arumugam, Paritha, Shukla, Samriddhi, Pradhan, Arun, Ustiyan, Vladimir, Milewski, David, Kalinichenko, Vladimir V., Kalin, Tanya V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353143/
https://www.ncbi.nlm.nih.gov/pubmed/32348194
http://dx.doi.org/10.1091/mbc.E19-07-0413