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PLK1 is required for chromosome compaction and microtubule organization in mouse oocytes

Errors during meiotic resumption in oocytes can result in chromosome missegregation and infertility. Several cell cycle kinases have been linked with roles in coordinating events during meiotic resumption, including polo-like kinases (PLKs). Mammals express four kinase-proficient PLKs (PLK1–4). Prev...

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Detalles Bibliográficos
Autores principales: Little, Tara M., Jordan, Philip W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353151/
https://www.ncbi.nlm.nih.gov/pubmed/32267211
http://dx.doi.org/10.1091/mbc.E19-12-0701