Therapeutic Delivery of rAAV sox9 via Polymeric Micelles Counteracts the Effects of Osteoarthritis-Associated Inflammatory Cytokines in Human Articular Chondrocytes

Osteoarthritis (OA) is a prevalent joint disease linked to the irreversible degradation of key extracellular cartilage matrix (ECM) components (proteoglycans, type-II collagen) by proteolytic enzymes due to an impaired tissue homeostasis, with the critical involvement of OA-associated pro-inflammato...

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Detalles Bibliográficos
Autores principales: Urich, Jonas, Cucchiarini, Magali, Rey-Rico, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353187/
https://www.ncbi.nlm.nih.gov/pubmed/32630578
http://dx.doi.org/10.3390/nano10061238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353187/
https://www.ncbi.nlm.nih.gov/pubmed/32630578
http://dx.doi.org/10.3390/nano10061238

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