Quantitative Analysis of Antibody Survival across the Infant Digestive Tract Using Mass Spectrometry with Parallel Reaction Monitoring

Orally delivered antibodies may be useful for the prevention of enteric pathogen infection, but to be effective they need to survive intact across digestion through the gastrointestinal tract. As a test case, we fed a recombinant human antibody, palivizumab, spiked into human milk to four infants an...

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Detalles Bibliográficos
Autores principales: Kim, Bum Jin, Lueangsakulthai, Jiraporn, Sah, Baidya Nath P., Scottoline, Brian, Dallas, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353590/
https://www.ncbi.nlm.nih.gov/pubmed/32526824
http://dx.doi.org/10.3390/foods9060759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353590/
https://www.ncbi.nlm.nih.gov/pubmed/32526824
http://dx.doi.org/10.3390/foods9060759

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