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Quantitative Analysis of Antibody Survival across the Infant Digestive Tract Using Mass Spectrometry with Parallel Reaction Monitoring
Orally delivered antibodies may be useful for the prevention of enteric pathogen infection, but to be effective they need to survive intact across digestion through the gastrointestinal tract. As a test case, we fed a recombinant human antibody, palivizumab, spiked into human milk to four infants an...
Autores principales: | Kim, Bum Jin, Lueangsakulthai, Jiraporn, Sah, Baidya Nath P., Scottoline, Brian, Dallas, David C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353590/ https://www.ncbi.nlm.nih.gov/pubmed/32526824 http://dx.doi.org/10.3390/foods9060759 |
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