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Nucleic acids in inclusion bodies obtained from E. coli cells expressing human interferon-gamma

BACKGROUND: Inclusion bodies (IBs) are protein aggregates in recombinant bacterial cells containing mainly the target recombinant protein. Although it has been shown that IBs contain functional proteins along with protein aggregates, their direct application as pharmaceuticals is hindered by their h...

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Detalles Bibliográficos
Autores principales: Krachmarova, Elena, Ivanov, Ivan, Nacheva, Genoveva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353671/
https://www.ncbi.nlm.nih.gov/pubmed/32652996
http://dx.doi.org/10.1186/s12934-020-01400-6