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Nucleic acids in inclusion bodies obtained from E. coli cells expressing human interferon-gamma
BACKGROUND: Inclusion bodies (IBs) are protein aggregates in recombinant bacterial cells containing mainly the target recombinant protein. Although it has been shown that IBs contain functional proteins along with protein aggregates, their direct application as pharmaceuticals is hindered by their h...
Autores principales: | Krachmarova, Elena, Ivanov, Ivan, Nacheva, Genoveva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353671/ https://www.ncbi.nlm.nih.gov/pubmed/32652996 http://dx.doi.org/10.1186/s12934-020-01400-6 |
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