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Prion peptide-mediated calcium level alteration governs neuronal cell damage through AMPK-autophagy flux

BACKGROUND: The distinctive molecular structure of the prion protein, PrPsc, is established only in mammals with infectious prion diseases. Prion protein characterizes either the transmissible pathogen itself or a primary constituent of the disease. Our report suggested that prion protein-mediated n...

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Detalles Bibliográficos
Autores principales: Moon, Ji-Hong, Park, Sang-Youel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353712/
https://www.ncbi.nlm.nih.gov/pubmed/32650778
http://dx.doi.org/10.1186/s12964-020-00590-1