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Prion peptide-mediated calcium level alteration governs neuronal cell damage through AMPK-autophagy flux
BACKGROUND: The distinctive molecular structure of the prion protein, PrPsc, is established only in mammals with infectious prion diseases. Prion protein characterizes either the transmissible pathogen itself or a primary constituent of the disease. Our report suggested that prion protein-mediated n...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353712/ https://www.ncbi.nlm.nih.gov/pubmed/32650778 http://dx.doi.org/10.1186/s12964-020-00590-1 |