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CPEB3 inhibits epithelial-mesenchymal transition by disrupting the crosstalk between colorectal cancer cells and tumor-associated macrophages via IL-6R/STAT3 signaling

BACKGROUND: Crosstalk between cancer cells and tumor-associated macrophages (TAMs) mediates tumor progression in colorectal cancer (CRC). Cytoplasmic polyadenylation element binding protein 3 (CPEB3) has been shown to exhibit tumor-suppressive role in CRC. METHODS: The expression of CPEB3, CD68, CD8...

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Detalles Bibliográficos
Autores principales: Zhong, Qian, Fang, Yuxin, Lai, Qiuhua, Wang, Shanci, He, Chengcheng, Li, Aimin, Liu, Side, Yan, Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353816/
https://www.ncbi.nlm.nih.gov/pubmed/32653013
http://dx.doi.org/10.1186/s13046-020-01637-4