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Roles of JNK/Nrf2 Pathway on Hemin-Induced Heme Oxygenase-1 Activation in MCF-7 Human Breast Cancer Cells

Heme oxygenase-1 (HO-1) is highly induced in various human disease states, including cancer, indicating that HO-1 is an emerging target of cancer therapy. In this study, we investigated that the mechanisms of hemin-induced HO-1 expression and its signaling pathways in human breast cancer cell. We us...

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Detalles Bibliográficos
Autores principales: Jang, Hye-Yeon, Hong, On-Yu, Chung, Eun-Yong, Park, Kwang-Hyun, Kim, Jong-Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353851/
https://www.ncbi.nlm.nih.gov/pubmed/32485912
http://dx.doi.org/10.3390/medicina56060268