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Baicalin Protects Human OA Chondrocytes Against IL-1β-Induced Apoptosis and ECM Degradation by Activating Autophagy via MiR-766-3p/AIFM1 Axis

BACKGROUND: Osteoarthritis (OA) is one of the most prevalent and degenerative diseases with complicated pathology including articular cartilage degradation, subchondral sclerosis and synovitis. Chondrocytes play a crucial role in maintaining cartilage integrity. METHODS: Primary chondrocytes were tr...

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Detalles Bibliográficos
Autores principales: Li, Zhi, Cheng, Jiangqi, Liu, Jiuxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353997/
https://www.ncbi.nlm.nih.gov/pubmed/32753846
http://dx.doi.org/10.2147/DDDT.S255823