Cargando…
Baicalin Protects Human OA Chondrocytes Against IL-1β-Induced Apoptosis and ECM Degradation by Activating Autophagy via MiR-766-3p/AIFM1 Axis
BACKGROUND: Osteoarthritis (OA) is one of the most prevalent and degenerative diseases with complicated pathology including articular cartilage degradation, subchondral sclerosis and synovitis. Chondrocytes play a crucial role in maintaining cartilage integrity. METHODS: Primary chondrocytes were tr...
Autores principales: | Li, Zhi, Cheng, Jiangqi, Liu, Jiuxiang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353997/ https://www.ncbi.nlm.nih.gov/pubmed/32753846 http://dx.doi.org/10.2147/DDDT.S255823 |
Ejemplares similares
-
LINC00623/miR-101/HRAS axis modulates IL-1β-mediated ECM degradation, apoptosis and senescence of osteoarthritis chondrocytes
por: Lü, Guohua, et al.
Publicado: (2020) -
Silencing of circ_0000205 mitigates interleukin-1β-induced apoptosis and extracellular matrix degradation in chondrocytes via targeting
miR-766-3p/ADAMTS5 axis
por: Li, Guowen, et al.
Publicado: (2022) -
Egr-1 mediates the suppressive effect of IL-1 on PPARg expression in human OA chondrocytes
por: Nebbaki, Sarah S, et al.
Publicado: (2012) -
miR-139 modulates MCPIP1/IL-6 expression and induces apoptosis in human OA chondrocytes
por: Makki, Mohammad Shahidul, et al.
Publicado: (2015) -
Egr-1 mediates the suppressive effect of IL-1 on PPARγ expression in human OA chondrocytes
por: Nebbaki, Salwa Sarah, et al.
Publicado: (2012)