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PRRX1 isoform PRRX1A regulates the stemness phenotype and epithelial-mesenchymal transition (EMT) of cancer stem-like cells (CSCs) derived from non-small cell lung cancer (NSCLC)

BACKGROUNDS: The 2 isoforms of paired-related homeobox 1 (PRRX1), PRRX1A and PRRX1B, are critical in regulating several kinds of cancers, and figure prominently in the maintenance of stemness and progression of epithelial-mesenchymal transition (EMT). However their differential expression in non-sma...

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Detalles Bibliográficos
Autores principales: Sun, Lei, Han, Tao, Zhang, Xinyu, Liu, Xiangli, Li, Peiwen, Shao, Mingrui, Dong, Siyuan, Li, Wenya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354111/
https://www.ncbi.nlm.nih.gov/pubmed/32676335
http://dx.doi.org/10.21037/tlcr-20-633