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Increased number of subclones in lung squamous cell carcinoma elicits overexpression of immune related genes
BACKGROUND: Intratumoral heterogeneity is a cause of drug resistance that leads to treatment failure. We investigated the clinical implication of intratumoral heterogeneity inferred from the number of subclones that constituted a tumor and reasoned the etiology of subclonal expansion using RNA seque...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354124/ https://www.ncbi.nlm.nih.gov/pubmed/32676328 http://dx.doi.org/10.21037/tlcr-19-589 |