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Increased number of subclones in lung squamous cell carcinoma elicits overexpression of immune related genes

BACKGROUND: Intratumoral heterogeneity is a cause of drug resistance that leads to treatment failure. We investigated the clinical implication of intratumoral heterogeneity inferred from the number of subclones that constituted a tumor and reasoned the etiology of subclonal expansion using RNA seque...

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Detalles Bibliográficos
Autores principales: Song, Myung Jin, Lee, Sang Hoon, Kim, Eun Young, Chang, Yoon Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354124/
https://www.ncbi.nlm.nih.gov/pubmed/32676328
http://dx.doi.org/10.21037/tlcr-19-589