Cargando…
应用CRISPR-Cas9基因编辑技术实现染色体大片段缺失
OBJECTIVE: Using CRISPR-Cas9 gene editing technology to achieve a number of genes co-deletion on the same chromosome. METHODS: CRISPR-Cas9 lentiviral plasmid that could induce deletion of Aloxe3-Alox12b-Alox8 cluster genes located on mouse 11B3 chromosome was constructed via molecular clone. HEK293T...
| Formato: | Online Artículo Texto |
|---|---|
| Lenguaje: | English |
| Publicado: |
Editorial office of Chinese Journal of Hematology
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354198/ https://www.ncbi.nlm.nih.gov/pubmed/28565744 http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2017.05.014 |