Gating of human TRPV3 in a lipid bilayer

The TRPV3 channel plays a critical role in skin physiology, and mutations in TRPV3 result in the development of a congenital skin disorder, Olmsted syndrome. Here we describe multiple cryo-electron microscopy structures of human TRPV3 reconstituted into lipid nanodiscs, representing distinct functio...

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Detalles Bibliográficos
Autores principales: Deng, Zengqin, Maksaev, Grigory, Rau, Michael, Xie, Zili, Hu, Hongzhen, Fitzpatrick, James A.J., Yuan, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354234/
https://www.ncbi.nlm.nih.gov/pubmed/32572252
http://dx.doi.org/10.1038/s41594-020-0428-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354234/
https://www.ncbi.nlm.nih.gov/pubmed/32572252
http://dx.doi.org/10.1038/s41594-020-0428-2

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