Bleeding is increased in amyloid precursor protein knockout mouse

BACKGROUND: Amyloid precursor protein (APP) is highly expressed in platelets. APP is the precursor to amyloid beta (Aβ) peptides that accumulate in cerebral amyloid angiopathy and plaques in Alzheimer disease. APP and its metabolites interact with many components of the coagulation system, and have...

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Detalles Bibliográficos
Autores principales: Mazinani, Nima, Strilchuk, Amy W., Baylis, James R., Hur, Woosuk S., Jefferies, Wilfred A., Kastrup, Christian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles: Hemostasis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354397/
https://www.ncbi.nlm.nih.gov/pubmed/32685890
http://dx.doi.org/10.1002/rth2.12375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354397/
https://www.ncbi.nlm.nih.gov/pubmed/32685890
http://dx.doi.org/10.1002/rth2.12375

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