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Protease: Serpin complexes to assess contact system and intrinsic pathway activation

Mounting evidence suggests that a variety of disease states are pathophysiologically related to activation of the contact system in vivo. The plasma contact system is composed of a cascade of serine proteases initiated by surface activation of factor XII, which can then proceed through a procoagulan...

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Detalles Bibliográficos
Autores principales: Henderson, Michael W., Noubouossie, Denis F., Ilich, Anton, Wilson, Kathy J., Pawlinski, Rafal, Monroe, Dougald M., Key, Nigel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354413/
https://www.ncbi.nlm.nih.gov/pubmed/32685887
http://dx.doi.org/10.1002/rth2.12389