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Porcine Epidemic Diarrhea Virus nsp15 Antagonizes Interferon Signaling by RNA Degradation of TBK1 and IRF3

Porcine epidemic diarrhea virus (PEDV) causes a porcine disease associated with swine epidemic diarrhea. The type I interferon (IFN-I or IFN α/β) is a key mediator of innate antiviral response during virus infection. Different antagonistic strategies have been identified and determined as to how PED...

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Detalles Bibliográficos
Autores principales: Wu, Yang, Zhang, Hongling, Shi, Zhaorong, Chen, Jianfei, Li, Mingwei, Shi, Hongyan, Shi, Da, Guo, Longjun, Feng, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354440/
https://www.ncbi.nlm.nih.gov/pubmed/32486349
http://dx.doi.org/10.3390/v12060599