Cargando…

Porcine Epidemic Diarrhea Virus nsp15 Antagonizes Interferon Signaling by RNA Degradation of TBK1 and IRF3

Porcine epidemic diarrhea virus (PEDV) causes a porcine disease associated with swine epidemic diarrhea. The type I interferon (IFN-I or IFN α/β) is a key mediator of innate antiviral response during virus infection. Different antagonistic strategies have been identified and determined as to how PED...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Yang, Zhang, Hongling, Shi, Zhaorong, Chen, Jianfei, Li, Mingwei, Shi, Hongyan, Shi, Da, Guo, Longjun, Feng, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354440/ https://www.ncbi.nlm.nih.gov/pubmed/32486349 http://dx.doi.org/10.3390/v12060599

Ejemplares similares

Stromal Antigen 2 Deficiency Induces Interferon Responses and Restricts Porcine Deltacoronavirus Infection
por: Wu, Yang, et al.
Publicado: (2022)

Broad antagonism of coronaviruses nsp5 to evade the host antiviral responses by cleaving POLDIP3
por: Wu, Yang, et al.
Publicado: (2023)

Porcine Epidemic Diarrhea Virus nsp7 Inhibits MDA5 Dephosphorylation to Antagonize Type I Interferon Production
por: Zhang, Jiansong, et al.
Publicado: (2023)

Suppression of type I interferon production by porcine epidemic diarrhea virus and degradation of CREB-binding protein by nsp1
por: Zhang, Qingzhan, et al.
Publicado: (2016)

Porcine deltacoronavirus E protein induces interleukin-8 production via NF-κB and AP-1 activation
por: Wu, Yang, et al.
Publicado: (2022)

Porcine Reproductive and Respiratory Syndrome Virus nsp11 Antagonizes Type I Interferon Signaling by Targeting IRF9
por: Wang, Dang, et al.
Publicado: (2019)

Molecular epidemiology of porcine epidemic diarrhea virus in China
por: Chen, Jianfei, et al.
Publicado: (2010)

Detection and Molecular Diversity of Spike Gene of Porcine Epidemic Diarrhea Virus in China
por: Chen, Jianfei, et al.
Publicado: (2013)

A New Neutralization Epitope in the Spike Protein of Porcine Epidemic Diarrhea Virus
por: Liu, Jianbo, et al.
Publicado: (2022)

Molecular Characterizations of Subcellular Localization Signals in the Nucleocapsid Protein of Porcine Epidemic Diarrhea Virus
por: Shi, Da, et al.
Publicado: (2014)

ATPase and helicase activities of porcine epidemic diarrhea virus nsp13
por: Ren, Jie, et al.
Publicado: (2021)

Expression and immunogenicity of nsp10 protein of porcine epidemic diarrhea virus
por: Zhu, Liting, et al.
Publicado: (2022)

Genetic variation of nucleocapsid genes of porcine epidemic diarrhea virus field strains in China
por: Chen, Jianfei, et al.
Publicado: (2013)

Identification of a conserved linear B-cell epitope in the M protein of porcine epidemic diarrhea virus
por: Zhang, Zhibang, et al.
Publicado: (2012)

Porcine deltacoronavirus nsp15 antagonizes interferon-β production independently of its endoribonuclease activity
por: Liu, Xiaorong, et al.
Publicado: (2019)

Identification of two novel B cell epitopes on porcine epidemic diarrhea virus spike protein
por: Sun, Dongbo, et al.
Publicado: (2008)

Immunogenicity and antigenic relationships among spike proteins of porcine epidemic diarrhea virus subtypes G1 and G2
por: Wang, Xiaobo, et al.
Publicado: (2015)

Identification of TBK1 complexes required for the phosphorylation of IRF3 and the production of interferon β
por: Bakshi, Siddharth, et al.
Publicado: (2017)

TANK-Binding Kinase 1 (TBK1) Isoforms Negatively Regulate Type I Interferon Induction by Inhibiting TBK1-IRF3 Interaction and IRF3 Phosphorylation
por: Hu, Yi Wei, et al.
Publicado: (2018)

Tumor suppressor p53 inhibits porcine epidemic diarrhea virus infection via interferon-mediated antiviral immunity
por: Hao, Zhichao, et al.
Publicado: (2019)

A porcine epidemic diarrhea virus strain with distinct characteristics of four amino acid insertion in the COE region of spike protein
por: Ji, Zhaoyang, et al.
Publicado: (2021)

Erratum to: Immunogenicity and antigenic relationships among spike proteins of porcine epidemic diarrhea virus subtypes G1 and G2
por: Wang, Xiaobo, et al.
Publicado: (2016)

Neutralization of genotype 2 porcine epidemic diarrhea virus strains by a novel monoclonal antibody
por: Liu, Jianbo, et al.
Publicado: (2017)

Nucleocapsid protein from porcine epidemic diarrhea virus isolates can antagonize interferon-λ production by blocking the nuclear factor-κB nuclear translocation
por: Shan, Ying, et al.
Publicado: (2018)

Porcine Epidemic Diarrhea Virus and Its nsp14 Suppress ER Stress Induced GRP78
por: Zeng, Wei, et al.
Publicado: (2023)

Metalloprotease ADAM17 regulates porcine epidemic diarrhea virus infection by modifying aminopeptidase N
por: Zhang, Jian, et al.
Publicado: (2018)

Swine Acute Diarrhea Syndrome Coronavirus Nucleocapsid Protein Antagonizes Interferon-β Production via Blocking the Interaction Between TRAF3 and TBK1
por: Zhou, Zhihai, et al.
Publicado: (2021)

Development of a rapid immunochromatographic strip test for the detection of porcine epidemic diarrhea virus specific SIgA in colostrum
por: Liu, Jianbo, et al.
Publicado: (2020)

Thymoquinone Suppresses IRF-3-Mediated Expression of Type I Interferons via Suppression of TBK1
por: Aziz, Nur, et al.
Publicado: (2018)

UBQLN2 Promotes the Production of Type I Interferon via the TBK1-IRF3 Pathway
por: Chen, Tianhong, et al.
Publicado: (2020)

ERRα negatively regulates type I interferon induction by inhibiting TBK1-IRF3 interaction
por: He, Xiang, et al.
Publicado: (2017)

Coronaviruses Nsp5 Antagonizes Porcine Gasdermin D-Mediated Pyroptosis by Cleaving Pore-Forming p30 Fragment
por: Shi, Fushan, et al.
Publicado: (2022)

Mutations in SARS-CoV-2 variant nsp6 enhance type-I interferon antagonism
por: Bills, Cody J., et al.
Publicado: (2023)

Porcine Epidemic Diarrhea
por: Peng, Ju-Yi, et al.
Publicado: (2016)

SARS-CoV-2 3C-like protease antagonizes interferon-beta production by facilitating the degradation of IRF3
por: Zhang, Wenwen, et al.
Publicado: (2021)

Broadly Antiviral Activities of TAP1 through Activating the TBK1-IRF3-Mediated Type I Interferon Production
por: Zhao, Jin, et al.
Publicado: (2021)

Impact of porcine circovirus type 2 on porcine epidemic diarrhea virus replication in the IPI-FX cell line depends on the order of infection
por: Zhang, Hao, et al.
Publicado: (2023)

Significant Interference with Porcine Epidemic Diarrhea Virus Pandemic and Classical Strain Replication in Small-Intestine Epithelial Cells Using an shRNA Expression Vector
por: Shi, Da, et al.
Publicado: (2019)

Resistance of Field-Isolated Porcine Epidemic Diarrhea Virus to Interferon and Neutralizing Antibody
por: Park, Jung-Eun, et al.
Publicado: (2022)

The cGAS/STING–TBK1–IRF Regulatory Axis Orchestrates a Primitive Interferon-Like Antiviral Mechanism in Oyster
por: Qiao, Xue, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_df0hqp8l8du55t8t2j2igh02hd