OnabotulinumtoxinA Displays Greater Biological Activity Compared to IncobotulinumtoxinA, Demonstrating Non-Interchangeability in Both In Vitro and In Vivo Assays

Differences in botulinum neurotoxin manufacturing, formulation, and potency evaluation can impact dose and biological activity, which ultimately affect duration of action. The potency of different labeled vials of incobotulinumtoxinA (Xeomin(®); 50 U, 100 U, or 200 U vials; incobotA) versus onabotul...

Descripción completa

Detalles Bibliográficos
Autores principales: Rupp, David, Nicholson, Greg, Canty, David, Wang, Joanne, Rhéaume, Catherine, Le, Linh, Steward, Lance E., Washburn, Mark, Jacky, Birgitte P., Broide, Ron S., Philipp-Dormston, Wolfgang G., Brin, Mitchell F., Brideau-Andersen, Amy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354455/
https://www.ncbi.nlm.nih.gov/pubmed/32545832
http://dx.doi.org/10.3390/toxins12060393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354455/
https://www.ncbi.nlm.nih.gov/pubmed/32545832
http://dx.doi.org/10.3390/toxins12060393

Ejemplares similares