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OnabotulinumtoxinA Displays Greater Biological Activity Compared to IncobotulinumtoxinA, Demonstrating Non-Interchangeability in Both In Vitro and In Vivo Assays
Differences in botulinum neurotoxin manufacturing, formulation, and potency evaluation can impact dose and biological activity, which ultimately affect duration of action. The potency of different labeled vials of incobotulinumtoxinA (Xeomin(®); 50 U, 100 U, or 200 U vials; incobotA) versus onabotul...
Autores principales: | Rupp, David, Nicholson, Greg, Canty, David, Wang, Joanne, Rhéaume, Catherine, Le, Linh, Steward, Lance E., Washburn, Mark, Jacky, Birgitte P., Broide, Ron S., Philipp-Dormston, Wolfgang G., Brin, Mitchell F., Brideau-Andersen, Amy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354455/ https://www.ncbi.nlm.nih.gov/pubmed/32545832 http://dx.doi.org/10.3390/toxins12060393 |
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