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An Anti-Cancer Peptide LVTX-8 Inhibits the Proliferation and Migration of Lung Tumor Cells by Regulating Causal Genes’ Expression in p53-Related Pathways

Spider venom has been found to show its anticancer activity in a variety of human malignancies, including lung cancer. In this study, we investigated the anti-cancer peptide toxin LVTX-8, with linear amphipathic alpha-helical conformation, designed and synthesized from the cDNA library of spider Lyc...

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Detalles Bibliográficos
Autores principales: Zhang, Peng, Yan, Yujie, Wang, Junting, Dong, Xiaoping, Zhang, Gaihua, Zeng, Yong, Liu, Zhonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354478/
https://www.ncbi.nlm.nih.gov/pubmed/32498425
http://dx.doi.org/10.3390/toxins12060367