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Characterization of Plaque Variants and the Involvement of Quasi-Species in a Population of EV-A71
Viral plaque morphologies in human cell lines are markers for growth capability and they have been used to assess the viral fitness and selection of attenuated mutants for live-attenuated vaccine development. In this study, we investigate whether the naturally occurring plaque size variation reflect...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354493/ https://www.ncbi.nlm.nih.gov/pubmed/32560288 http://dx.doi.org/10.3390/v12060651 |