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PRMT5 Is Required for Bovine Leukemia Virus Infection In Vivo and Regulates BLV Gene Expression, Syncytium Formation, and Glycosylation In Vitro

Bovine leukemia virus (BLV) is the causative agent of enzootic bovine leukosis, which is the most common neoplastic disease of cattle and is closely related to human T-cell leukemia viruses. We investigated the role of a new host protein, PRMT5, in BLV infection. We found that PRMT5 is overexpressed...

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Detalles Bibliográficos
Autores principales: Assi, Wlaa, Hirose, Tomoya, Wada, Satoshi, Matsuura, Ryosuke, Takeshima, Shin-nosuke, Aida, Yoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354529/
https://www.ncbi.nlm.nih.gov/pubmed/32560231
http://dx.doi.org/10.3390/v12060650