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Deficits in Mitochondrial Spare Respiratory Capacity Contribute to the Neuropsychological Changes of Alzheimer’s Disease

Alzheimer’s disease (AD) is diagnosed using neuropsychological testing, supported by amyloid and tau biomarkers and neuroimaging abnormalities. The cause of neuropsychological changes is not clear since they do not correlate with biomarkers. This study investigated if changes in cellular metabolism...

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Detalles Bibliográficos
Autores principales: Bell, Simon M., De Marco, Matteo, Barnes, Katy, Shaw, Pamela J., Ferraiuolo, Laura, Blackburn, Daniel J., Mortiboys, Heather, Venneri, Annalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354560/
https://www.ncbi.nlm.nih.gov/pubmed/32365522
http://dx.doi.org/10.3390/jpm10020032