Therapeutic Targeting of Aristolochic Acid Induced Uremic Toxin Retention, SMAD 2/3 and JNK/ERK Pathways in Tubulointerstitial Fibrosis: Nephroprotective Role of Propolis in Chronic Kidney Disease

The nephrotoxicity of aristolochic acids (AAs), p-cresyl sulfate (PCS) and indoxyl sulfate (IS) were well-documented, culminating in tubulointerstitial fibrosis (TIF), advanced chronic kidney disease (CKD) and fatal urothelial cancer. Nonetheless, information regarding the attenuation of AAs-induced...

Descripción completa

Detalles Bibliográficos
Autores principales: Chang, Jia-Feng, Hsieh, Chih-Yu, Lu, Kuo-Cheng, Chen, Yue-Wen, Liang, Shih-Shin, Lin, Chih-Cheng, Hung, Chi-Feng, Liou, Jian-Chiun, Wu, Mai-Szu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354564/
https://www.ncbi.nlm.nih.gov/pubmed/32498221
http://dx.doi.org/10.3390/toxins12060364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354564/
https://www.ncbi.nlm.nih.gov/pubmed/32498221
http://dx.doi.org/10.3390/toxins12060364

Ejemplares similares