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Therapeutic Targeting of Aristolochic Acid Induced Uremic Toxin Retention, SMAD 2/3 and JNK/ERK Pathways in Tubulointerstitial Fibrosis: Nephroprotective Role of Propolis in Chronic Kidney Disease

The nephrotoxicity of aristolochic acids (AAs), p-cresyl sulfate (PCS) and indoxyl sulfate (IS) were well-documented, culminating in tubulointerstitial fibrosis (TIF), advanced chronic kidney disease (CKD) and fatal urothelial cancer. Nonetheless, information regarding the attenuation of AAs-induced...

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Detalles Bibliográficos
Autores principales:	Chang, Jia-Feng, Hsieh, Chih-Yu, Lu, Kuo-Cheng, Chen, Yue-Wen, Liang, Shih-Shin, Lin, Chih-Cheng, Hung, Chi-Feng, Liou, Jian-Chiun, Wu, Mai-Szu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354564/ https://www.ncbi.nlm.nih.gov/pubmed/32498221 http://dx.doi.org/10.3390/toxins12060364

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