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BLI-Based Functional Assay in Phage Display Benefits the Development of a PD-L1-Targeting Therapeutic Antibody

The therapeutic functionality of the antibodies from phage display is verified after an initial screening. Several immunological assays such as ELISA, flow cytometry, the western blot, and surface plasmon resonance (SPR) assay are commonly used; the IgG-format antibody is usually preferred to verify...

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Detalles Bibliográficos
Autores principales: Choi, Jong Rip, Kim, Min Jung, Tae, Nara, Wi, Tae Min, Kim, Se-Ho, Lee, Eung Suk, Kim, Dae Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354572/
https://www.ncbi.nlm.nih.gov/pubmed/32630442
http://dx.doi.org/10.3390/v12060684