Zearalenone-Induced Interaction between PXR and Sp1 Increases Binding of Sp1 to a Promoter Site of the eNOS, Decreasing Its Transcription and NO Production in BAECs

Zearalenone (ZEN) is a non-steroidal mycotoxin that has various toxicological impacts on mammalian health. Here, we found that ZEN significantly affected the production of nitric oxide (NO) and the expression of endothelial NO synthase (eNOS) of bovine aortic endothelial cells (BAECs). A promoter an...

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Detalles Bibliográficos
Autores principales: Lee, Hyeon-Ju, Park, Jung-Hyun, Oh, Se-Young, Cho, Du-Hyong, Kim, Suji, Jo, Inho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354576/
https://www.ncbi.nlm.nih.gov/pubmed/32630586
http://dx.doi.org/10.3390/toxins12060421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354576/
https://www.ncbi.nlm.nih.gov/pubmed/32630586
http://dx.doi.org/10.3390/toxins12060421

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