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Identification of Combinations of Protein Kinase C Activators and Histone Deacetylase Inhibitors that Potently Reactivate Latent HIV

Combination antiretroviral therapy (cART) is successful in maintaining undetectable levels of HIV in the blood; however, the persistence of latent HIV reservoirs has become the major barrier for a HIV cure. Substantial efforts are underway in finding the best latency-reversing agents (LRAs) to purge...

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Detalles Bibliográficos
Autores principales: Curreli, Francesca, Ahmed, Shahad, Victor, Sofia M. Benedict, Debnath, Asim K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354613/
https://www.ncbi.nlm.nih.gov/pubmed/32503121
http://dx.doi.org/10.3390/v12060609