Cargando…
Identification of Combinations of Protein Kinase C Activators and Histone Deacetylase Inhibitors that Potently Reactivate Latent HIV
Combination antiretroviral therapy (cART) is successful in maintaining undetectable levels of HIV in the blood; however, the persistence of latent HIV reservoirs has become the major barrier for a HIV cure. Substantial efforts are underway in finding the best latency-reversing agents (LRAs) to purge...
Autores principales: | Curreli, Francesca, Ahmed, Shahad, Victor, Sofia M. Benedict, Debnath, Asim K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354613/ https://www.ncbi.nlm.nih.gov/pubmed/32503121 http://dx.doi.org/10.3390/v12060609 |
Ejemplares similares
-
Latent HIV in primary T lymphocytes is unresponsive to histone deacetylase inhibitors
por: Sahu, Gautam K, et al.
Publicado: (2011) -
Discovery of Highly Potent Small Molecule Pan-Coronavirus Fusion Inhibitors
por: Curreli, Francesca, et al.
Publicado: (2023) -
Discovery of Highly Potent Fusion Inhibitors with Potential Pan-Coronavirus Activity That Effectively Inhibit Major COVID-19 Variants of Concern (VOCs) in Pseudovirus-Based Assays
por: Curreli, Francesca, et al.
Publicado: (2021) -
Stapled Peptides Based on Human Angiotensin-Converting Enzyme 2 (ACE2) Potently Inhibit SARS-CoV-2 Infection In Vitro
por: Curreli, Francesca, et al.
Publicado: (2020) -
Discovery of potent histone deacetylase inhibitors with modified phenanthridine caps
por: Fan, Wenli, et al.
Publicado: (2021)