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Oxidative Stress and Neuroinflammation Potentiate Each Other to Promote Progression of Dopamine Neurodegeneration

Parkinson's disease (PD) is a chronic and complex disease of the central nervous system (CNS). Progressive loss of dopamine (DA) neurons in midbrain substantia nigra is considered to be the main cause of PD. The hallmark of PD pathology is the formation of Lewy bodies and the deposition of α-sy...

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Detalles Bibliográficos
Autores principales: He, Jingyi, Zhu, Guofu, Wang, Guoqing, Zhang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354668/
https://www.ncbi.nlm.nih.gov/pubmed/32714488
http://dx.doi.org/10.1155/2020/6137521