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Transcriptome analysis of the zebrafish atoh7−/− Mutant, lakritz, highlights Atoh7‐dependent genetic networks with potential implications for human eye diseases

Expression of the bHLH transcription protein Atoh7 is a crucial factor conferring competence to retinal progenitor cells for the development of retinal ganglion cells. Several studies have emerged establishing ATOH7 as a retinal disease gene. Remarkably, such studies uncovered ATOH7 variants associa...

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Detalles Bibliográficos
Autores principales: Covello, Giuseppina, Rossello, Fernando J., Filosi, Michele, Gajardo, Felipe, Duchemin, Anne‐Laure, Tremonti, Beatrice F., Eichenlaub, Michael, Polo, Jose M., Powell, David, Ngai, John, Allende, Miguel L., Domenici, Enrico, Ramialison, Mirana, Poggi, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354691/
https://www.ncbi.nlm.nih.gov/pubmed/32676583
http://dx.doi.org/10.1096/fba.2020-00030