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TSLP and IL‐33 reciprocally promote each other's lung protein expression and ILC2 receptor expression to enhance innate type‐2 airway inflammation

BACKGROUND: The epithelial cell‐derived danger signal mediators thymic stromal lymphopoietin (TSLP) and IL‐33 are consistently associated with adaptive Th2 immune responses in asthma. In addition, TSLP and IL‐33 synergistically promoted group 2 innate lymphoid cell (ILC2) activation to induce innate...

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Detalles Bibliográficos
Autores principales: Toki, Shinji, Goleniewska, Kasia, Zhang, Jian, Zhou, Weisong, Newcomb, Dawn C., Zhou, Baohua, Kita, Hirohito, Boyd, Kelli L., Peebles, Ray S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354889/
https://www.ncbi.nlm.nih.gov/pubmed/31975538
http://dx.doi.org/10.1111/all.14196