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ARPP-19 Mediates Herceptin Resistance via Regulation of CD44 in Gastric Cancer
PURPOSE: As the first-line drug for treatment of HER2-positive metastatic gastric cancer (GC), Herceptin exhibits significant therapeutic efficacy. However, acquired resistance of Herceptin limits the therapeutic benefit of gastric cancer patients, in which the molecular mechanisms remain to be furt...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354958/ https://www.ncbi.nlm.nih.gov/pubmed/32753897 http://dx.doi.org/10.2147/OTT.S253841 |