Cargando…
ARPP-19 Mediates Herceptin Resistance via Regulation of CD44 in Gastric Cancer
PURPOSE: As the first-line drug for treatment of HER2-positive metastatic gastric cancer (GC), Herceptin exhibits significant therapeutic efficacy. However, acquired resistance of Herceptin limits the therapeutic benefit of gastric cancer patients, in which the molecular mechanisms remain to be furt...
Autores principales: | Gao, Xiang, Lu, Changwen, Chen, Changyu, Sun, Kang, Liang, Qixin, Shuai, Jianfeng, Wang, Xiaoming, Xu, Yuxing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354958/ https://www.ncbi.nlm.nih.gov/pubmed/32753897 http://dx.doi.org/10.2147/OTT.S253841 |
Ejemplares similares
-
The Interaction Mechanism of Intrinsically Disordered PP2A Inhibitor Proteins ARPP-16 and ARPP-19 With PP2A
por: Thapa, Chandan, et al.
Publicado: (2021) -
Increased ARPP-19 Expression Is Associated with Hepatocellular Carcinoma
por: Song, Haiyan, et al.
Publicado: (2014) -
The study of the determinants controlling Arpp19 phosphatase-inhibitory activity reveals an Arpp19/PP2A-B55 feedback loop
por: Labbé, Jean Claude, et al.
Publicado: (2021) -
(1)H, (13)C and (15)N NMR chemical shift assignments of cAMP-regulated phosphoprotein-19 and -16 (ARPP-19 and ARPP-16)
por: Thapa, Chandan J., et al.
Publicado: (2020) -
ENSA and ARPP19 differentially control cell cycle progression and development
por: Hached, Khaled, et al.
Publicado: (2019)